The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Ulrike Hass, Uwe Dünnbier, Gudrun Massmann and Asaf Pekdeger.
Simultaneous determination of psychoactive substances and their metabolites in aqueous matrices by ultrahigh-performance liquid chromatography-tandem mass spectrometry, Anal. Methods, 2011, 3, 902.