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15Beyond Trastuzumab: Second-Generation Targeted Therapies for HER-2-positive Breast Cancer, Drugs for HER-2-positive Breast Cancer Multitarget Control of Drug Impact: A Therapeutic Imperative in Cancer Systems Biology, Biomolecular Interfaces Epistructure-Based Design of Drugs with Controlled Promiscuity, Physics at the Biomolecular Interface Fulfilling a Therapeutic Imperative in Cancer Treatment: Control of Multi-target Drug Impact, Transformative Concepts for Drug Design: Target Wrapping Putting the Brakes on Cancer, Pharmaceutical Innovation Molecular target-based cancer therapy: tyrosine kinase inhibitors, International Journal of Clinical Oncology The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells, Breast Cancer Research and Treatment An update on molecularly targeted therapies in second- and third-line treatment in non-small cell lung cancer: focus on EGFR inhibitors and anti-angiogenic agents, Clinical and Translational Oncology Sensitivity of Melanoma Cells to EGFR and FGFR Activation but Not Inhibition is Influenced by Oncogenic BRAF and NRAS Mutations, Pathology & Oncology Research